Interesting twist on biosynthesis of polycyclic xanthone antibiotics

Post date: Apr 22, 2016 7:30:17 AM

Congratulations Delin You and co-workers at Shanghai Jiao Tong University and Chengdu University! Our collaborative work revealed an interesting mechanism for anthraquinone-to-xanthone transformation in the biosynthesis of xantholipin and other polycyclic xanthone antibiotics. 

The paper titled "A Multifunctional Monooxygenase XanO4 Catalyzes Xanthone Formation in Xantholipin Biosynthesis via a Cryptic Demethoxylation" has just went online. 

Please check it out and share (limited time free access until June 10): http://www.sciencedirect.com/science/article/pii/S2451945616300915